Ping Mamiya, Ph.D.

Research Scientist

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Bio

Why is learning a new language so much easier at a young age? Although it is known that human brains continue to develop well into adulthood, it remains a grand challenge to understand the biological basis underlying critical periods for second language learning. With globalization of the world, second language skills are not only important for students to master in schools, but also necessary for adults to keep up with increasing multilingual society.

 
To investigate this question, my research integrates multi-modal brain imaging and genetic sequencing analyses to uncover the neurogenetic basis underlying critical periods for language acquisition. This innovative approach will provide us new insights into why learning a new language becomes difficult later in life, and why some people learn better and faster than others. This information will contribute to human development and help design treatment plans for learning or cognitive deficits in neurodevelopmental disorders.

 

RESEARCH INTERESTS


My research interest is to uncover the neurogenetic basis underlying critical periods for cognitive development and language learning. With this information in hand, I would like to contribute to the promotion of human development. I collaborate with scientist and clinicians in various fields and bridge my findings to further the understanding of cognitive or learning deficits in brain or developmental disorders.

 

CV

EDUCATION


2006            Ph.D.            Biopsychology and Behavioral Neuroscience
                                         Rutgers – The State University of New Jersey, New Brunswick, NJ, USA
2004            M.S.             Biopsychology and Behavioral Neuroscience
                                         Rutgers – The State University of New Jersey, New Brunswick, NJ, USA
1997            B.S.              Psychology
                                         Kaoshiung Medical College, Kaoshiung, Taiwan

PROFESSIONAL TRAINING


2019            NIH Regional Seminar            National Institute of Health            Research grant funding

2017            High-Troughput Biology: From Sequence to Networks           Cold Spring Harbor Laboratory
                                                                                                                    Cold Spring Harbor, NY, USA
2016            Elements of R                                                                          Summer Institute,
                                                                                                                     University of Washington
                                                                                                                     Seattle, WA, USA
2016            Association Mapping:GWAS and Sequencing Data                 Summer Institute,
                                                                                                                     University of Washington
                                                                                                                     Seattle, WA, USA
2016            Future Faculty Workshop                                                         University of Washington
                                                                                                                     Seattle, WA, USA
2015            Presentation Excellence                                                          University of Washington
                                                                                                                     Seattle, WA, USA
2015            Python Programming                                                               University of Washington
                                                                                                                     Seattle, WA, USA
2013            FSL course                                                                               FMRIB Centre,
                                                                                                                     University of Oxford
                                                                                                                     Redmond, WA, USA

AWARDS


2018            Postdoctoral Travel Award (2018) Office of Postdoctoral Affairs                                                               University of Washington

2017            Helmsley Fellowship                                                               Cold Spring Harbor Laboratory
2016            Scholarship to attend Summer Institute                                  University of Washington,
                                                                                                                    Department of Biostatistics
2016            Scholarship to attend Gila in Health and Disease meeting     Cold Spring Harbor Laboratory
2016            Postdoctoral Travel Award                                                      University of Washington,
                                                                                                                    Office of Postdoctoral Affairs
2015            Postdoctoral Fellow Award                                                     Cognitive Neuroscience Society
1997            Ambassador Scholarship Award                                             Rotary International

GRANTS


2019             The Paros Foundation Award, 2019                    
2016            Small Grant Project (Role:P1)                    Institute of Translational Health Sciences (ITHS),
                                                                                       University of Washington, Seattle, WA

UNIVERSITY TEACHING EXPERIENCES


Department of Linguistics, Rutgers University – New Brunswick, NJ, USA                      1999 - 2000
Teaching assistant for the introductory Mandarin courses; grading students; works; and leading discussion sessions.

Department of Anatomy, National Yang-Ming University, Taipei Taiwan                            1996 - 1997
Assistant lecturer for the Gross anatomy, and Human Neuroanatomy lab courses for 150 medical and dental students; performing dissection on human cadaver; designing study materials; and leading discussion sessions.

INVITED TALKS


1. Neurogenetic basis underlying language learning – implications for critical periods (2019).
Department of Radiology, John Hopkins University. Baltimore, Maryland, USA
Host: Richard Edden, Ph.D.

2. Genetic variations associated with brain development in 7-month-old infants (2018).
Tracking Infant Brain Development workshop. International Research Center for NeuroIntelligence. The University of Tokyo. Tokyo, Tokyo, Japan
Host: Takao Hensch, Ph.D.

3. Neurogentic factors involved in the closing of critical periods for second language learning (2018).
Department of Psychology, University of Washington. Seattle, WA, USA
Host: Andrea Stocco, Ph.D.

4. Using ITHS to combine neural, genetic and behavioral data on human language learning (2017).
Center on Human Development and Disability – Clinical Translational Core (CHDD-CTC) Research Symposium. Seattle, WA, USA

5. Brain structures and genetic variations jointly predict second language learning in adults (2016).
International Mind, Brain and Education Conference. Toronto, Ontario, Canada
Chair: Mary Helen Immordino-Yang, Ph.D.

6. Integrated Brain Imaging Center (2015).
University of Washington Seattle, WA, USA
Host: Dan Peterson, Ph.D.

7. The Cognition and Cortical Dynamics Laboratory (2015).
University of Washington. Seattle, WA, USA
Host: Chantel Prat, Ph.D.

8. National Institute of Health (2015).
Bethesda, MD, USA.
Host: R. Douglas Fields, Ph.D.
 

OUTREACH ACTIVITIES


2016 - 2017. Math and Science committee. Jane Addams Middle School.
Responsibilities: Organizing outreach programs from various departments at the University of Washington to participate in school’s annual math and science fair.

2012 – 2015. Guest lecturer Sacajawea Elementary School, Seattle, WA, USA
Responsibilities: Coordinating with school teachers to provide lectures for K-5 students on topics related to science and math using PowerPoint slides and hand-on demonstrations; brining outreach programs from various departments at the University of Washington to participate in annual math and science fair.

2010 - 2012. Guest lecturer Camino Grove Elementary School, Arcadia, CA, USA
Responsibilities: Coordinating with school teachers to provide lectures for kindergarten and 1st grade students on topics related to science and math using PowerPoint slides.

PUBLIC ADVISORY COMMITTEE


2012 - 2016. Co-chair of the Math and Science Committee. Sacajawea Elementary School Seattle, WA, USA
Responsibilities: Establishing cost-free academic enrichment programs for K-5 students; Organizing and implementing after-school programs to assist under-privileged students.

Publications

WORKS IN PROGRESS


1. Mamiya, PC, Richards, T, Lee AKC Lee, Edden, R, Stein M, and Kuhl PK. Reduced GABA levels during tasks are associated with impaired attention control skills in adults with ADHD. (in preparation)

2. Mamiya, PC, Richards, T, Edden, R, Stein, M, and Kuhl PK. Methyphenidate treatment changes GABA inhibition in the anterior cingulate cortex in children with ADHD. (in preparation)

3. Mamiya, PC, Lee Su-In, and Kuhl PC. COMT gene is involved in prefrontal myelination in children and adolsecents. (in preparation)

PUBLICATIONS


Mamiya, PC, Richards, TL, Corrigan, N, and Kuhl, PK. The strength of ventral tegmental area connectivity to the left dorsal striatum is correlated with conflict monitoring skills. (under review)

Mamiya, PC, Richards, TL, Kuhl, PK. (2018). Right forceps minor and anterior thalamic radiation predict executive function skills in young bilingual adults. Frontier in Psychology February. DOI: 10.3389/fpsyg.2018.00118.

Mamiya, PC, Matray-Devoti, J, Fisher, H, Wagner, GC. (2017). Mice increased target biting behaviors 24 h after co-administration of alcohol and fluoxetine. Brain Research May 1662:110-115.

Mamiya, PC, Richards, T, Coe, BP, Eichler, EE and Kuhl, PK. Brain white matter structure and COMT gene are linked to second language learning in adults. Proceedings of the National Academy of Sciences of the United States of America. 2016 June 28; 113(26): 7259-54.

Mamiya, PC, Hennesey, Z, Zhou, RP, Wagner, GC. Changes in attack behavior and activity in EphA5 knockout Mice. Brain Research 2008 Apr 18: 1205:91-9.

Ahmed I, Liu HY, Mamiya PC, Ponery AS, Babu AN, Weik T, Schindler M, Meiners S. J. Three-dimensional nanofibrillar surfaces covalently modified with tenascin-C-derived peptides enhance neuronal growth in vitro. Biomed Mater Res A. 2006 Mar 15; 76(4)851-60.

Mamiya, PC, Matray-Devoti, J, Fisher, H, Wagner, GC. Mice increased target biting behaviors 24 hours after co-administration of alcohol and fluoxetine. (under minor revision).

Works in Progress

Mamiya, PC, Richards, TL, and Kuhl, PK. Ventral Tegmental Area and Cingulum Pathways Mediate Second Language Listening and Reading skills in Chinese Young Adults. (in preparation).

Mamiya, PC, Ahmed, I, Schindler, Wagner, GC and Meiners, S. Nanofiber Matrix Enhances Neurite Outgrowth and Survival of Dopamine Progenitor Cells. (in preparation).

CONFERENCE PRESENTATIONS


Mamiya, PC, Richards, T, Lee AKC Lee, Edden, R, Stein M, and Kuhl PK. (2019). Reduced GABA levels during tasks is associated with impaired attention control skills in adults with ADHD. 5th International Symposium on GABA and advanced MRS. Park City, Utah, USA.

Mamiya, PC, Richards, TL, and Kuhl, PK. (2018). VTA connectivity to anterior versus posterior brain regions show opposite patterns of association with attention control in second language learners. Gordon Research Conference/Seminar  – Neurobiology of Cognition, Newry, Maine, USA.

Mamiya, PC, Richards, TL, and Kuhl, PK. Characterizing a possible role of oligodendrocyte dependent myelination in second language learning – a brain imaging study. Glia in Health and Disease. Cold Spring Harbor Laboratory. Cold Spring Harbor, New York, USA (2016).

Mamiya, PC, Richards, TL, Coe, B, Eichler EE, and Kuhl, PK. Linking gene, brain and behavior in a study of second language learning. Annual meeting for the Cognitive Neuroscience Society. San Francisco, California, USA (2015).

Mamiya, PC, Richards, TL, Coe, B, Eichler, EE, and Kuhl, PK. Val158Met polymorphism in COMT affects the brain’s white matter properties during second language immersion. Annual meeting for The American Society of Human Genetics. Washington DC, USA (2015).

Mamiya, PC. Neural and genetic correlates of second language acquisition. The Ready Mind Project. University of Washington, Washington, USA (2014).

Mamiya, PC., Meiners, S, Schindler, M and Wagner, GC. Nanofiber matrix enhances neurite outgrowth of dopamine progenitor cells in culture. Annual meeting for the Society for Neuroscience. San Diego, California, USA (2004).

Mamiya, PC, Zhou, RP, Wagner, GC. Locomotor Activity in EphA5 Knockout Mice. Annual meeting for the Society for Neuroscience. New Orleans, Louisiana, USA (2003).

Mamiya, PC, Hennesey, Z, Zhou, RP, Wagner, GC. Aggression in EphA5 Knockout Mice. Annual meeting for the Society for Neuroscience. Orlando, Florida, USA (2002).

Mamiya, PC, Matray-Devoti, J, Fisher, H, Wagner, G.C. Delayed Increase in Defensive Aggression Following Fluoxetine. Annual meeting for the Society for Neuroscience. San Diego, California, USA (2001).

INVITED TALKS


2016 Brain structures and genetic variations jointly predict second language learning in adults.
         2016 International Mind, Brain and Education Conference, Toronto, Canada.

Contact

Phone Number: 
(206) 221-6415
Email: 
pcmamiya@uw.edu

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